10/7/2023 0 Comments Too much taurine side effects![]() “We need a clinical study to show that it can demonstrate these benefits in us, as well,” says Barzilai. He told the Telegraph that the human-adjusted version of this daily dosage would work out at between 3g-6g of taurine, although this has yet to be tested. To begin with, the mice in Yadav’s study were given high doses of taurine – 1g per kilogram of body weight per day. However, scientists caution that we still need to know more about the effects of taurine in humans. “They had more blood-glucose and insulin tolerance, and they also seemed to be less anxious and fearful in their behaviour, and their memory was working better.” “Taurine supplementation reduced their body-fat percentage, increased their bone density and made their muscles function better – they had better muscle strength, better neuromuscular co-ordination and could run for longer on a treadmill,” he says. Yadav says it is notable that when taurine was given to middle-aged mice, it led to multiple health benefits. One of the reasons for this is that taurine appears to be capable of enhancing the function of mitochondria, the power factories within our cells that give us energy. Multiple clinical trials have since shown that it can offer benefit, helping them to become more active. Research suggests that it acts across multiple organ systems, protecting the brain by regulating the amount of calcium within nerve cells – a nutrient that is crucial for memory and other cognitive functions – as well as controlling inflammation in the heart and blood vessels.īack in the 1980s, Japanese doctors began giving taurine supplements to patients who had suffered heart failure, in an attempt to improve their exercise capacity. While amino acids usually help build various proteins in the body, taurine has a markedly different function. We’re seeing more and more gerotherapeutics starting to emerge.” How does taurine work in the body? “I’m very excited for any progress in this field. “As well as extending the lifespan and healthspan of animals, taurine seems to target most of the hallmarks of ageing,” says Nir Barzilai, founding director of the Institute for Ageing Research at the Albert Einstein College of Medicine, in New York, and a pioneer of anti-ageing drugs, or gerotherapeutics. This is based on various studies in animals or by studying cells in the lab. Similar benefits have been identified by researchers at Victoria University, in Melbourne, who found that taurine shows potential for improving cardiovascular health, as well as preventing the harmful accumulation of cholesterol and fat within the arteries. When Yadav and his colleagues examined taurine in 12,000 European adults over the age of 60, they found that higher levels were linked to fewer cases of type 2 diabetes, less obesity, reduced hypertension and lower inflammation. ![]() Taurine has long been popular with bodybuilders and athletes, who take it as a supplement to try and control their body temperature and reduce muscle fatigue during competition.īut more and more research is suggesting that maintaining sufficient levels of taurine may be crucial for health in later life. To me, it’s exciting to see if by boosting taurine, we can alter some of the ageing processes.” Why is everyone so excited about taurine? ![]() “Babies are very dependent on taurine for growth, and it’s found in very high levels in breast milk, but in old age, our taurine levels are 80 per cent lower. “With age, taurine levels in our body start to decline for reasons we don’t fully understand,” he says. Vijay Yadav, an assistant professor at Columbia University, in New York, who led the study, told the Telegraph that the findings suggest that taurine could be a way of reversing some of the biological processes of ageing. The supplement prevented weight gain, increased bone density and improved their immune systems. Similar benefits were found when taurine was given to middle-aged rhesus macaques for six months. Intriguingly, not only did the animals live longer, but they seemed to be healthier. Last week, an international team of researchers published a study in the prestigious journal Science where they showed that giving taurine to middle-aged mice increased their lifespan by 10 to 12 per cent – the equivalent of an extra decade in humans. Scientists have been studying taurine for 200 years, but its real potential has only been uncovered relatively recently. From Jeff Bezos to Google founders Sergey Brin and Larry Page, the world’s billionaires, and their quest for immortality, have been driving a renewed interest in longevity supplements over the past two years.īut for all their wacky investments – from stem cells to blood transfusions from teenagers – could the real elixir of life turn out to be an amino acid that is commonly found in Red Bull and other energy drinks?
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